Dow Jumps Over 200 Points; Cleveland-Cliffs Shares Jump After Q3 Results – Celcuity (NASDAQ:CELC), Adaptimmune Therapeutics (NASDAQ:ADAP)

U.S. stocks traded higher this morning, with the Dow Jones Industrial Average gaining more than 200 points on Monday. Following the market opening Tuesday, the Dow rose 0.47% to 46,407.15, the NASDAQ gained 0.93% to 22,890.22, and the S&P 500 advanced 0.61% to 6,704.61.

Leading and Lagging Sectors

Energy shares jumped by 1.2% on Monday, while consumer staples stocks slipped 0.1%.

Top Headline

Cleveland-Cliffs Inc. (NYSE: CLF) shares surged about 17% on Monday after the company reported third-quarter 2025 results. The steelmaker posted an adjusted loss of 45 cents per share, beating expectations for a 48-cent loss. Revenue came in at $4.73 billion, below the $4.90 billion consensus but higher than $4.57 billion in the year-ago period.

Notable Movers

Equities Trading Up

• Replimune Group, Inc. (NASDAQ: REPL) jumped 105% to $9.31 after the FDA accepted its resubmission of the Biologics License Application for RP1 in combination with nivolumab for advanced melanoma, with a PDUFA date of April 10, 2026.
• Celcuity Inc. (NASDAQ: CELC) rallied 55% to $80.50 after presenting Phase 1 data at ESMO 2025 showing its gedatolisib plus darolutamide combination achieved a 9.1-month median rPFS in mCRPC, with a favorable safety profile and no treatment-related discontinuations.
• GSI Technology, Inc. (NASDAQ: GSIT) gained 70% to $8.64 after the company reported that its associative processing unit compute-in-memory architectures can match GPU-level performance for large-scale AI applications.

Equities Trading Down

• MingZhu Logistics Holdings Limited (NASDAQ: YGMZ) fell 78% to $0.1962.
• Adaptimmune Therapeutics plc (NASDAQ: ADAP) declined 71% to $0.0586 after announcing plans to delist from the Nasdaq.
• United Homes Group, Inc. (NASDAQ: UHG) dropped 39% to $2.5944 after concluding its review of strategic alternatives and announcing director resignations.

Commodities

Oil traded down 1.2% to $56.88, while gold rose 2.8% to $4,330.00. Silver gained 2.1% to $51.165, and copper increased 0.8% to $5.0105.

Global Markets

Europe

European shares were broadly higher. The STOXX 600 rose 0.8%, Spain’s IBEX 35 advanced 1.4%, London’s FTSE 100 added 0.4%, Germany’s DAX 40 gained 1.6%, and France’s CAC 40 edged up 0.2%.

Asia Pacific

Asian markets closed higher on Monday. Japan’s Nikkei 225 gained 3.37%, Hong Kong’s Hang Seng index rose 2.42%, China’s Shanghai Composite increased 0.63%, and India’s BSE Sensex advanced 0.49%.

Economic Calendar

The CB Leading Index will be released today.