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Must-Have Cryptos for May 2025: Bitcoin’s Mainstream Rise and Top Altcoin Picks

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4 Coins You Must Own in May 2025 as Bitwise CEO Says Bitcoin Has Officially Gone Mainstream, Thanks to Institutional Adoption

The cryptocurrency market of 2025 is witnessing a transformative era characterized by institutional acceptance. Bitwise CEO Hunter Horsley recently proclaimed that Bitcoin has “officially gone mainstream,” supporting the growing consensus among financial giants. With major institutions such as BlackRock, Fidelity, and Vanguard embracing digital currencies, retail traders are recalibrating their investments and searching for the next big opportunity. As Web3 merges with traditional finance, several altcoins are poised for substantial growth. Four cryptocurrencies stand out as ones to watch in May 2025.

Bitcoin – The Cornerstone of the Crypto Economy

Bitcoin continues to be the bedrock of the crypto economy. Once met with skepticism, Bitcoin is now widely recognized as a secure digital store of value and an effective hedge against inflation. Institutional investors no longer merely dabble in Bitcoin; they have integrated it as a core component of their portfolios. The inclusion of Bitcoin in pension plans, sovereign wealth funds, and ETFs marks a “new era” for this asset class as noted by Bitwise CEO Hunter Horsley.

Currently valued at around $91,345, Bitcoin has surged by over 45% in the last six months. Although its returns might not match those of certain soaring altcoins, its stability and liquidity over the long term make it a must-have asset for any serious investor. The broader narrative positioning Bitcoin as ‘digital gold’ continues to attract capital inflows, especially with increasing regulatory clarity in significant economies such as the U.S. and Europe. As more nations contemplate Bitcoin as a treasury asset, its long-term appeal remains strong.

Ethereum – Leading the Way in Decentralized Applications

Ethereum stands as the pivotal platform for decentralized applications, courtesy of its Layer 1 blockchain. The successful completion of significant upgrades such as Merge and proto-danksharding (EIP-4844) demonstrates Ethereum’s commitment to resolving fee and throughput challenges. These updates pave the way for the expansion of DeFi systems, gaming platforms, NFT trading, and enterprise blockchain implementations.

While Ethereum was valued at $1,699 in April 2025, trailing its historical peak, the network’s fundamental strength reached new highs. Ethereum acts as the foundation for leading financial institutions, while governments explore tokenization systems for real estate, bond markets, and identity verification based on Ethereum. Ethereum’s prospects receive momentum from the burgeoning Layer 2 ecosystem led by Arbitrum, Optimism, and Base. Unlike Bitcoin that dominates the institutional trust space, Ethereum leads in usability and functional benefits.

Solana – The Developer-Friendly Blockchain

Solana is emerging as a developer favorite for low-cost, high-performance blockchain solutions. Its resilience in both bear and bull markets, complemented by recent upgrades to its validator infrastructure, has enhanced uptime and decentralization. Solana’s ability to support consumer-facing applications, including decentralized social networks, gaming, and NFTs, renders it one of the most developer-friendly blockchains available.

Currently priced at roughly $143, Solana presents significant upside potential below its 2021 levels. It has quickly become a formidable contender to host the next generation of mass-market blockchain applications. With new institutional capital flowing into Solana through structured investment products and index funds, it is gaining acknowledgment as a blue-chip cryptocurrency, set to continue its growth into late 2025.

Rexas Finance (RXS) – A Star in Asset Tokenization

Among emerging altcoin stars, Rexas Finance (RXS) is gaining prominence as a leader in asset tokenization. While other projects recycle old ideas, Rexas Finance taps into a multi-trillion-dollar market by enabling fractional ownership of traditionally illiquid assets like real estate, fine art, and commodities. Through blockchain, these assets are broken down into RXS tokens, democratizing wealth creation opportunities that were previously limited to the wealthy.

A key highlight for Rexas is its impressive presale success, raising over $48,000,000 with more than 92% of the tokens in the last stage sold out. This substantial pre-launch demand reflects growing investor confidence. Set to be listed on numerous tier-1 exchanges in June 2025, early evaluations from crypto analysts suggest potential 100x to 200x valuation growth post-launch. Regulatory compliance and institutional partnerships set Rexas apart, with frameworks tailored to international finance laws, enhancing adoption potential among retail investors and institutions alike.

The Rapid Evolution of Cryptocurrency in 2025

The cryptocurrency ecosystem is evolving swiftly, with 2025 heralding substantial innovation. Bitcoin’s institutional adoption lays the groundwork for next-generation portfolios, while Ethereum and Solana form the infrastructure for decentralized innovation. Rexas Finance, on the other hand, offers an exhilarating promise of exponential growth by pioneering tokenized exposure to real-world assets. Its substantial presale volumes and future tier-1 exchange listings, coupled with an innovative vision of democratizing wealth creation, place it firmly at the top of the list for portfolio inclusion.

As the global movement toward a more inclusive financial system gains momentum, Rexas Finance is forging a path forward. For investors seeking not only stability but also significant value breakthroughs, RXS could represent the best crypto bet today.

Natalie Kimura
Natalie Kimurahttps://www.businessorbital.com/
Natalie Kimura is a business correspondent known for her in-depth interviews and feature articles. With a background in International Business and a passion for global economic affairs, Natalie has traveled extensively, providing her with a unique perspective on international trade and global market dynamics. She started her career in Tokyo, contributing to various financial journals, and later moved to London to expand her expertise in European markets. Natalie's expertise lies in international trade agreements, foreign investment patterns, and economic policy analysis.

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